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Medchemexpress LLC trans-Cinnamic acid | 140-10-3 | 148.16 | 1 G
Supplier: Medchemexpress LLC HYN06101G
Trans-Cinnamic acid is a natural antimicrobial with a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen A. sobria, SY-AS1. It shows moderate inhibition on rainbow trout intestinal isolates A. sobria SY-AS3 and S. baltica, SY-S145, gill isolate F. spartansii SY-FS1, and fish pathogens A. salmonicida ATCC 33658, Listonella anguillarum, SY-L24, V. crassostreae SY-VC10, and Y. ruckeri E42. This acid is more effective on bacteria when the pH of the culture media is not neutralized. It also inhibits M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse bone marrow macrophage with an IC50 > 100 μM.
- Natural antimicrobial
- Effective against various fish pathogens and nonpathogenic isolates
- More effective on bacteria in non-neutralized pH culture media
- Inhibits osteoclast differentiation
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