trans-Diamminedichloroplatinum(II), Pt 64.5% min

Description

CAS: 14913-33-8 | Cl2H6N2Pt | 300.05 g/mol

trans-Diamminedichloroplatinum(II) acts as a reversible RNA-protein cross-linking agent. It is also used in plating baths. It reacts with DNA after hydrolysis to get both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 14913-33-8
• Molecular Formula: Cl2H6N2Pt
• Molecular Weight (g/mol): 300.05
• MDL Number: MFCD00011623
• InChI Key: LXZZYRPGZAFOLE-UHFFFAOYSA-L
• Synonym: trans-dichlorodiamineplatinum ii, azane; dichloroplatinum, h6cl2n2pt, ia call, ddp-h, platinol tn, cl.2h3n.pt, platinum ii chloride diamine, spectrum1502107, cisplatin jp17/usp/inn
• PubChem CID: 5702198
• ChEBI: CHEBI:27899
• IUPAC Name: azane;dichloroplatinum
• SMILES: N.N.Cl[Pt]Cl

• Melting Point: 340°C (dec.)
• Color: Yellow
• Physical Form: Crystalline
• Quantity: 0.25 g
• Linear Formula: PtCl₂(NH₃)₂
• Solubility Information: Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water.
• Formula Weight: 300.06
• Concentration or Composition (by Analyte or Components): Pt 64.5% min.
• Odor: Odorless
• Chemical Name or Material: trans-Diamminedichloroplatinum(II)

Safety and Handling

Hazard Category	H301+H311+H331-H317-H318-H334-H340-H351
Hazard Statement	GHS H Statement H334-H341-H335-H315-H319-H317 May cause allergy or asthma symptoms or breathing difficulties if inhaled. Suspected of causing genetic defects. May cause respiratory irritation. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction.
Precautionary Statement	P201-P202-P261-P264b-P270-P271-P272-P280g-P281-P285-P301+P310-P302+P352-P304+P340-P305+P351+P338-P308+P313-P310-P311-P312-P330-P333+P313-P361-P363-P501c
DOTInformation	Hazard Class: 6.1; Packaging Group: II
EINECSNumber	238-980-9
RTECSNumber	TP2455000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only