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AdipoGen trans-Indole-3-acrylic acid
SDP

Supplier:  AdipoGen AGCR13677G001

Encompass_Preferred

Chemical. CAS 29953-71-7. Formula C11H9NO2. MW 187.2. Synthetic. Inflammation suppressor. Tryptophan metabolite produced by human microbiota intestinal commensale Peptostreptococcus sp. Involved in keeping the intestinal barrier intact and works as anti-inflammatory molecule. Patients with Inflammatory bowel Disease IBD have an altered microbiota, with less Peptostreptococcus sp., and therefore reduced production of trans-indole-3-acrylic acid. Chromophoric L-Trp analog used to probe the allosteric properties of the internal aldimine of tryptophan synthas. Also shown to be a moderate inhibitor of tryptophan synthase, trypothan-2,3-dioxygenase, indoleamine-2,3-dioxygenase, L-dopachrome isomerase and xanthine oxidase. Reagent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize and analyze polyphenols and synthetic polymers.

Catalog No. 50-256-2238


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