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Enzo Life Sciences trans-Ned-19 (0.5mg)
SDP

Supplier:  Enzo Life Sciences ALX270503MC05

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Cell permeable, selective and potent inhibitor of nicotinic acid adenine dinucleotide phosphate (NAADP) receptor in mammalian cells and sea urchin eggs. Blocks NAADP signaling. Inhibits Ca2+ release: trans-Ned-19 (IC50 = 6nM); cis-Ned-19 (IC50 = 800nM). [32P] NAADP binding: trans-Ned-19 (IC50 = 0.4nM); cis-Ned-19 (IC50 = 15µM).Inhibits Ca2+ release from lysosomes. Noncompetitive antagonist. Fluorescent. Alternative name: 1-(3-((4-(2-Fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid. Purity: ≥97% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO or 100% ethanol. Long Term Storage: -20°C.

Catalog No. 50-200-8627


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