PYROJAS CORPORATION HiTE-NK™ Lentiviral Transduction Enhancer for Primary NK Cells, 10 mg ~200 Reactions, CAR-NK Cell Therapy Reagent, Natural Killer Cell Engineering, NK-92 iPSC-NK Compatible, Self-Inactivating TFP, Polybrene Alternative, Spinoculation-Free, RUO

Supplier:  PYROJAS CORPORATION HITENK10MG

HiTE-NK™ is a high-efficiency lentiviral transduction enhancer specifically engineered for primary human Natural Killer (NK) cells—one of the most challenging cell types to transduce in cell and gene therapy. As a bi-functional Transient Fusion-Promoting Peptide (TFP), HiTE™ concentrates lentivirus at the NK cell membrane to drive efficient gene transfer, then self-inactivates within hours to preserve NK viability, cytotoxicity, and effector function. A breakthrough alternative to polybrene (hexadimethrine bromide), LentiBOOST, RetroNectin coating, and spinoculation, HiTE-NK™ delivers up to 33.3% transduction efficiency (12.5× vs. polybrene) with >90% viability—where polybrene causes >80% NK viability loss.Applications: CAR-NK cell therapy, cytokine-armored NK (IL-15, IL-21), checkpoint receptor knockdown (NKG2A, KIR), allogeneic NK manufacturing.Cell types: primary NK, NK-92, iPSC-derived NK.Specs: 10 mg (~200 rxn); 10× (400 μM) stock; −80°C; RUO; PyrOjas Corp.

Catalog No. NC3972848