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PYROJAS CORPORATION HiTE-NK™ Lentiviral Transduction Enhancer for Primary NK Cells, 50 mg ~1,000 Reactions, Process Development Pack, CAR-NK Cell Therapy Manufacturing, Natural Killer Cell Engineering, Self-Inactivating TFP, Polybrene Alternative, GMP-Compatible, RUO

Catalog No. NC3972851
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HiTE-NK™ is a high-efficiency lentiviral transduction enhancer specifically engineered for primary human Natural Killer (NK) cells, supplied in a process-development pack size for scaled CAR-NK manufacturing and allogeneic cell therapy bioprocess. As a bi-functional Transient Fusion-Promoting Peptide (TFP), HiTE™ concentrates lentivirus at the NK cell membrane to drive efficient gene transfer, then self-inactivates within hours to preserve NK viability, cytotoxicity, and effector function. A breakthrough alternative to polybrene (hexadimethrine bromide), LentiBOOST, RetroNectin coating, and spinoculation, HiTE-NK™ delivers up to 33.3% transduction efficiency (12.5× vs. polybrene) with >90% viability—where polybrene causes >80% NK viability loss.Applications: CAR-NK, cytokine-armored NK (IL-15, IL-21), checkpoint knockdown (NKG2A, KIR).Cell types: primary NK, NK-92, iPSC-derived NK.Specs: 50 mg (~1,000 rxn); 10× (400 μM); −80°C; RUO; PyrOjas Corp.

Catalog No. NC3972851 Supplier PYROJAS CORPORATION Supplier No. HITENK50MG
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HiTE-NK™ is a high-efficiency lentiviral transduction enhancer specifically engineered for primary human Natural Killer (NK) cells, supplied in a process-development pack size for scaled CAR-NK manufacturing and allogeneic cell therapy bioprocess. As a bi-functional Transient Fusion-Promoting Peptide (TFP), HiTE™ concentrates lentivirus at the NK cell membrane to drive efficient gene transfer, then self-inactivates within hours to preserve NK viability, cytotoxicity, and effector function. A breakthrough alternative to polybrene (hexadimethrine bromide), LentiBOOST, RetroNectin coating, and spinoculation, HiTE-NK™ delivers up to 33.3% transduction efficiency (12.5× vs. polybrene) with >90% viability—where polybrene causes >80% NK viability loss.Applications: CAR-NK, cytokine-armored NK (IL-15, IL-21), checkpoint knockdown (NKG2A, KIR).Cell types: primary NK, NK-92, iPSC-derived NK.Specs: 50 mg (~1,000 rxn); 10× (400 μM); −80°C; RUO; PyrOjas Corp.

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