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Apexbio Technology LLC Tranylcypromine hydrochloride 1986-47-6 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B75145.1
Tranylcypromine hydrochloride (CAS 1986-47-6) is a small molecule inhibitor that irreversibly targets monoamine oxidase (MAO) isoforms A and B demonstrating mechanism-based inhibition with Ki values of 101 9 M for MAO A and 16 M for MAO B and corresponding IC50 values of 2 3 M and 0 95 M Additionally tranylcypromine acts as a time-dependent irreversible inhibitor of lysine-specific demethylase 1 (LSD1) an amine oxidase homolog with structural similarities to MAOs exhibiting a Ki of 242 M and an IC50 of 20 7 M This compound is widely utilized in studies investigating MAO and LSD1 enzymatic functions epigenetic regulation and monoamine metabolism
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