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Medchemexpress LLC Tranylcypromine hydrochloride | 1986-47-6 | 99.9% | 169.66 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY17447A100MG

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Tranylcypromine hydrochloride is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). It inhibits LSD1, MAO A, and MAO B with IC50s of 20.7, 2.3, and 0.95 μM, respectively, and can be used for the research of depression.

  • Irreversible inhibitor of lysine-specific demethylase 1 and monoamine oxidase.
  • Inhibits LSD1, MAO A, and MAO B with IC50s of 20.7, 2.3, and 0.95 μM, respectively.
  • Used for research on depression.
  • Inhibits histone and nucleosomal demethylation.
  • Shows specific derepression of OCT4 transcription.
  • Decreases LPS-mediated microglial activation and proinflammatory cytokine COX-2 and IL-6 levels in wild-type mice.
  • Down-regulates Aβ-mediated microglial activation in 5xFAD mice.

Catalog No. 50-003-86546


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