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Medchemexpress LLC Tranylcypromine (hydrochloride) | 1986-47-6 | 99.9% | 169.66 | 250 MG
Supplier: Medchemexpress LLC 250MGHY17447A
Tranylcypromine hydrochloride functions as an irreversible inhibitor of both lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). This compound demonstrates inhibitory effects on LSD1, MAO A, and MAO B, exhibiting IC50 values of 20.7, 2.3, and 0.95 μM, respectively. It is utilized for research related to depression.
- Irreversible inhibitor of lysine-specific demethylase 1.
- Irreversible inhibitor of monoamine oxidase (MAO).
- Shows inhibitory activity against MAO A (IC50 2.3 μM) and MAO B (IC50 0.95 μM).
- Inhibits LSD1 with an IC50 of 20.7 μM.
- Useful in depression research.
- Decreases LPS-mediated microglial activation.
- Reduces pro-inflammatory cytokine levels.
- Down-regulates Aβ-mediated microglial activation in relevant models.
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