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Bachem TRAP-14 Trifluoroacetate
SDP

Supplier:  Bachem 4031275.0001

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TRAP-14 Trifluoroacetate, H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH, 137339-65-2, C81H118N20O23, Mr 1739.95, 1mg. PAR-1 (1-14) (human), Thrombin Receptor Activator Peptide 14, Proteinase Activated Receptor 1 (1-14) (human), Thrombin Receptor (1-14) (human), Coagulation Factor II Receptor (1-14) (human), Thrombin Related Peptide. Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation.

Catalog No. 50-260-176


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