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Medchemexpress LLC Triacetylresveratrol | 42206-94-0 | 354.35 | 250 MG
Supplier: Medchemexpress LLC 250MGHYN1410
Triacetylresveratrol is an acetylated analog of Resveratrol. It decreases the phosphorylation of STAT3 and NF-κB in a dose- and time-dependent manner in PANC-1 and BxPC-3 cells, demonstrating anticancer effects. It significantly down-regulates the anti-apoptotic Bcl-2 family protein Mcl-1 and up-regulates the pro-apoptotic Bcl-2 family proteins Bim and Puma. Triacetylresveratrol inhibits cell viability and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner.
- STAT3/NF-κB inhibitor
- Decreases the phosphorylation of STAT3 and NF-κB
- Exhibits anticancer effects
- Significantly down-regulates the anti-apoptotic Bcl-2 family protein Mcl-1
- Up-regulates the pro-apoptotic Bcl-2 family proteins Bim and Puma
- Inhibits cell viability and induces apoptosis of pancreatic cancer cells in a concentration and incubation time-dependent manner
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