Trichloroacetic anhydride, 95%

Description

CAS: 4124-31-6 | C4Cl6O3 | 308.741 g/mol

Trichloroacetic anhydride is used as a derivatization reagent involved in the analysis of amphetamine,methamphetamine and 3,4-methylenedioxymethamphetamine. It is also used in the determination of the metabolites of l-alpha-acetylmethadol (LAAM), such as noracetylmethadol, dinoracetylmethadol, methadol and normethadol by electron capture gas-liquid chromatography. It is used in the synthesis of trichloroacetonylpyridine by reacting with 2-methyl-pyridine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trichloroacetic anhydride is used as a derivatization reagent involved in the analysis of amphetamine,methamphetamine and 3,4-methylenedioxymethamphetamine. It is also used in the determination of the metabolites of l-alpha-acetylmethadol (LAAM), such as noracetylmethadol, dinoracetylmethadol, methadol and normethadol by electron capture gas-liquid chromatography. It is used in the synthesis of trichloroacetonylpyridine by reacting with 2-methyl-pyridine.

Solubility
Miscible with ether and acetic acid.

Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong bases with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 4124-31-6
• Molecular Formula: C4Cl6O3
• Molecular Weight (g/mol): 308.741
• MDL Number: MFCD00000793
• InChI Key: MEFKFJOEVLUFAY-UHFFFAOYSA-N
• Synonym: trichloroacetic anhydride, acetic acid, trichloro-, anhydride, acetic acid, 2,2,2-trichloro-, 1,1'-anhydride, acmc-1aliy, perchloroacetic anhydride, bis trichloroacetic anhydride, trichloroacetic acid anhydride, 2,2,2-trichloroacetic anhydride, trichloroacetyl 2,2,2-trichloroacetate
• PubChem CID: 20079
• IUPAC Name: (2,2,2-trichloroacetyl) 2,2,2-trichloroacetate
• SMILES: C(=O)(C(Cl)(Cl)Cl)OC(=O)C(Cl)(Cl)Cl

• Density: 1.69
• Boiling Point: 98°C to 100°C (11 mmHg)
• Refractive Index: 1.484
• Quantity: 250 g
• UN Number: UN3265
• Beilstein: 980355
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with ether and acetic acid.
• Formula Weight: 308.76
• Percent Purity: 95%
• Chemical Name or Material: Trichloroacetic anhydride

Safety and Handling

Hazard Category	H314-H335
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Hazard Class: 8; Packaging Group: I
EINECSNumber	223-925-3
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only