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Apexbio Technology LLC Triclosan 3380-34-5 1g
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Supplier:  Apexbio Technology LLC C40351000

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Triclosan (CAS 3380-34-5) is a small-molecule inhibitor targeting enoyl-acyl carrier protein reductase (ENR/FabI) a key enzyme involved in bacterial fatty acid synthesis It is designed to inhibit lipid biosynthesis thereby disrupting bacterial growth Triclosan exerts its biological activity primarily through inhibition of FabI In cell-based studies Triclosan demonstrates inhibitory activity with IC50 values of 2 M for Escherichia coli FabI and 10 M for the Gly93 Val FabI mutant It also induces apoptosis in cultured rat neural stem cells Based on these pharmacological properties Triclosan holds research potential in antimicrobial mechanism studies antimicrobial resistance and disease models involving cell apoptosis and inflammation

Catalog No. 50-000-89449


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