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Medchemexpress LLC Trifluridine | 70-00-8 | MFCD00006534 | 99.9% | C10H11F3N2O5 | 1 ML
Supplier: Medchemexpress LLC HYA006110MM/1ML
Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor that suppresses DNA synthesis. It is an antiviral molecule used in research for HSV, rhabdovirus, and orthopoxvirus infections. Trifluridine induces cell apoptosis and autophagy. It also functions as an anticancer agent for studies involving metastatic colorectal cancer and gastrointestinal tumors.
- Irreversible and orally active thymidylate synthase inhibitor
- Suppresses DNA synthesis
- Antiviral for HSV, rhabdovirus, and orthopoxvirus infections
- Induces cell apoptosis and autophagy
- Functions as an anticancer agent for metastatic colorectal cancer and gastrointestinal tumors
- Inhibits proliferation in various cancer cell lines
- Shows antitumor activity in human colorectal intraperitoneal xenograft model
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