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Medchemexpress LLC Trilaciclib hydrochloride | 1977495-97-8 | >98.0% | 519.47 g/mol | C24H32Cl2N8O | 1 G
SDP

Catalog No. 5000248221
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Trilaciclib hydrochloride is the hydrochloride salt of trilaciclib, a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor used in preclinical research to study cell-cycle regulation and to evaluate protection against chemotherapy-induced myelosuppression.

  • Inhibits CDK4 and CDK6 with low-nanomolar potency (IC50 ≈ 1 nM and 4 nM).
  • Aqueous solubility ~0.96 mg/mL after ultrasonic treatment and acidification to pH 1.
  • Molecular weight 519.47 g/mol.
  • Store sealed at 4°C; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
  • Commonly provided in small masses suitable for stock solution preparation.
  • Reported purity ≥98% in supplier listings.
  • Used to investigate mitigation of chemotherapy-induced myelosuppression in vitro and in vivo models.

Catalog No. 50-002-48221 Supplier Medchemexpress LLC Supplier No. HY101467A1G
May include imposed supplier surcharges.
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Trilaciclib hydrochloride is the hydrochloride salt of trilaciclib, a potent cyclin-dependent kinase 4/6 (CDK4/6) inhibitor used in preclinical research to study cell-cycle regulation and to evaluate protection against chemotherapy-induced myelosuppression.

  • Inhibits CDK4 and CDK6 with low-nanomolar potency (IC50 ≈ 1 nM and 4 nM).
  • Aqueous solubility ~0.96 mg/mL after ultrasonic treatment and acidification to pH 1.
  • Molecular weight 519.47 g/mol.
  • Store sealed at 4°C; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
  • Commonly provided in small masses suitable for stock solution preparation.
  • Reported purity ≥98% in supplier listings.
  • Used to investigate mitigation of chemotherapy-induced myelosuppression in vitro and in vivo models.

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