Medchemexpress LLC Trimebutine maleate | 34140-59-5 | 99.7% | 1 G

Supplier:  Medchemexpress LLC HYB0380A1G

Trimebutine maleate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. It inhibits L-type Ca2+ and large-conductance calcium-activated potassium channels, blocking ion influx and efflux. It also targets Toll-like receptors, suppressing signals and inhibiting LPS-induced IRAK1, ERK1/2, JNK, and NF-κB activation for anti-inflammatory effects. It induces tumor cell apoptosis via AKT/ERK pathway inhibition and prevents excessive smooth muscle contraction, making it useful for gastrointestinal disorder studies.

• Multi-target inhibitor and opioid receptor agonist
• Exhibits antimuscarinic activity
• Blocks calcium influx and potassium ion efflux
• Suppresses Toll-like receptor signals
• Provides anti-inflammatory effects
• Induces tumor cell apoptosis
• Inhibits excessive smooth muscle contraction
• Useful in gastrointestinal disorder research

Catalog No. 50-004-07156