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Medchemexpress LLC Trimebutine maleate | 34140-59-5 | 99.7% | 1 G
SDP

Catalog No. 5000407156
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Trimebutine maleate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. It inhibits L-type Ca2+ and large-conductance calcium-activated potassium channels, blocking ion influx and efflux. It also targets Toll-like receptors, suppressing signals and inhibiting LPS-induced IRAK1, ERK1/2, JNK, and NF-κB activation for anti-inflammatory effects. It induces tumor cell apoptosis via AKT/ERK pathway inhibition and prevents excessive smooth muscle contraction, making it useful for gastrointestinal disorder studies.

  • Multi-target inhibitor and opioid receptor agonist
  • Exhibits antimuscarinic activity
  • Blocks calcium influx and potassium ion efflux
  • Suppresses Toll-like receptor signals
  • Provides anti-inflammatory effects
  • Induces tumor cell apoptosis
  • Inhibits excessive smooth muscle contraction
  • Useful in gastrointestinal disorder research

Catalog No. 50-004-07156 Supplier Medchemexpress LLC Supplier No. HYB0380A1G
May include imposed supplier surcharges.
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Trimebutine maleate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. It inhibits L-type Ca2+ and large-conductance calcium-activated potassium channels, blocking ion influx and efflux. It also targets Toll-like receptors, suppressing signals and inhibiting LPS-induced IRAK1, ERK1/2, JNK, and NF-κB activation for anti-inflammatory effects. It induces tumor cell apoptosis via AKT/ERK pathway inhibition and prevents excessive smooth muscle contraction, making it useful for gastrointestinal disorder studies.

  • Multi-target inhibitor and opioid receptor agonist
  • Exhibits antimuscarinic activity
  • Blocks calcium influx and potassium ion efflux
  • Suppresses Toll-like receptor signals
  • Provides anti-inflammatory effects
  • Induces tumor cell apoptosis
  • Inhibits excessive smooth muscle contraction
  • Useful in gastrointestinal disorder research

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