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Medchemexpress LLC Trimetazidine-d8 dihydrochloride | 1219795-37-5 | 99.9% | 1 MG
Supplier: Medchemexpress LLC HYB0968S1MG
Trimetazidine-d8 dihydrochloride is a deuterium labeled compound that acts as a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, inhibiting β-oxidation of free fatty acid (FFA). It is an effective antianginal and cytoprotective agent, possessing anti-oxidant, anti-inflammatory, antinociceptive, and gastroprotective properties. It also triggers autophagy and is a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor.
- Can be used as a tracer
- Internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable isotope-labeled compound with deuterium incorporated
- Affects pharmacokinetic and metabolic profiles
- For research use only
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