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Cayman Chemical TrImethoprIm-d3 1mg

Supplier: Cayman Chemical 261191 MG

An inhibitor of NF-KB (EC50 0.2 M in an NF-KB reporter gene assay) inhibits replication of human avian and swine influenza virus strains in MDCK cells in a concentration-dependent manner reversibly inhibits replication of H5N1 and H7N7 avian influenza virus strains in human A549 cells reduces viral mRNA and production of IL-6 and CXCL10/IP-10 in the lungs of H5N1 infected mice (15 mg/kg i.p.) protective against H5N1 and H7N7 infection in mice when administered for 7 days prior to or up to 4 days post infection
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