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Medchemexpress LLC Trimethylamine N-oxide (dihydrate) | 62637-93-8 | 98.0% | 111.14 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY10891510MM/1ML

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Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite derived from dietary choline and other trimethylamine-containing nutrients. It induces inflammation by activating the ROS/NLRP3 inflammasome. It also accelerates fibroblast-myofibroblast differentiation and triggers cardiac fibrosis by activating the TGF-β/smad2 signaling pathway. This compound is intended for research use only.

  • Gut microbe-dependent metabolite.
  • Induces inflammation via ROS/NLRP3 inflammasome activation.
  • Accelerates fibroblast-myofibroblast differentiation.
  • Induces cardiac fibrosis through TGF-β/smad2 signaling pathway activation.
  • Useful for creating cardiovascular and metabolic disease models in animals.

Catalog No. 50-003-46023


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