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Medchemexpress LLC Trimethylamine n-oxide dihydrate | 62637-93-8 | 98.0% | 111.14 | 50 MG
Supplier: Medchemexpress LLC HY10891550G
Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite derived from dietary choline and other trimethylamine-containing nutrients. It is known to induce inflammation by activating the ROS/NLRP3 inflammasome. Additionally, this compound accelerates fibroblast-myofibroblast differentiation and promotes cardiac fibrosis through the activation of the TGF-β/smad2 signaling pathway. It is intended for research use only and not for patient use.
- Gut microbe-dependent metabolite
- Induces inflammation via ROS/NLRP3 inflammasome activation
- Accelerates fibroblast-myofibroblast differentiation
- Induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway
- Found in marine organisms, offering protection against adverse environmental effects (temperature, salinity, high urea, hydrostatic pressure)
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