ProSci HRSP12 Recombinant Protein

Catalog No.	Quantity
16-594-194	0.05 mg

Catalog No. 16-594-194 Supplier ProSci Supplier No. 912360050

Description

Recombinant Protein

This recombinant protein can be used for biological assays. For research use only.

Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.

Specifications

• Accession Number: P52758
• For Use With (Application): Not Available
• Gene ID (Entrez): 10247
• Molecular Weight (g/mol): 16.7 kDa
• Quantity: 0.05 mg
• Source: E. coli
• Common Name: reactive intermediate imine deaminase A homolog
• Gene Symbol: RIDA
• Product Type: Recombinant Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: N-6 His tag
• Content And Storage: Store at -20°C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Form: Lyophilized
• Purity or Quality Grade: >95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
• Synonym: Ribonuclease UK114, 14.5 kDa Translational Inhibitor Protein, p14.5, Heat-Responsive Protein 12, UK114 Antigen Homolog, HRSP12, PSP