Trimethylsilyl azide, 94%

Description

CAS: 4648-54-8 | C3H9N3Si | 115.21 g/mol

Trimethylsilyl azide is used as an azidonation reagent for amines, amides, aldehydes and ketones. It is involved in the preparation of alfa- and beta-siloxy azides from carbonyl compounds and epoxides. It is also used in the preparation of heterocyclic compounds and also acts as an effective substitute for hydrazoic acid. Further, it is used in the Oseltamivir total synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylsilyl azide is used as an azidonation reagent for amines, amides, aldehydes and ketones. It is involved in the preparation of alfa- and beta-siloxy azides from carbonyl compounds and epoxides. It is also used in the preparation of heterocyclic compounds and also acts as an effective substitute for hydrazoic acid. Further, it is used in the Oseltamivir total synthesis.

Solubility
Miscible with toluene, dichloromethane, diethyl ether and most organic solvents.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.

Specifications

Chemical Identifiers

• CAS: 4648-54-8
• Molecular Formula: C3H9N3Si
• Molecular Weight (g/mol): 115.21
• MDL Number: MFCD00001986
• InChI Key: SEDZOYHHAIAQIW-UHFFFAOYSA-N
• Synonym: trimethylsilyl azide, silane, azidotrimethyl, trimethylsilylazide, azido trimethyl silane, ccris 8048, tms azide, tms-azide, trimethyl silylazide, trimethylsilyl-azide, azido trimethylsilane
• PubChem CID: 78378
• SMILES: C[Si](C)(C)N=[N+]=[N-]

• Melting Point: -95°C
• Density: 0.872
• Boiling Point: 95°C to 99°C
• Flash Point: 6°C (42°F)
• Refractive Index: 1.414
• Quantity: 5 g
• UN Number: UN1992
• Beilstein: 1903730
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with toluene,dichloromethane,diethyl ether and most organic solvents.
• IUPAC Name: azidotrimethylsilane
• Formula Weight: 115.21
• Percent Purity: 94%
• Chemical Name or Material: Trimethylsilyl azide

Safety and Handling

Hazard Category	H225-H301+H311+H331
Hazard Statement	GHS H Statement H225-H300-H310-H330 Highly flammable liquid and vapor. Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P310-P303+P361+P353-P304+P340-P311-P312-P330-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, TOXIC, N.O.S.
EINECSNumber	225-078-5
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only