Trimethylsilyl cyanide, 97%

Catalog No.	Quantity
AAA1959822	100 g
AAA1959806	5 g
AAA1959814	25 g

Catalog No. AAA1959822 Supplier Thermo Scientific Chemicals Supplier No. A1959822

Description

CAS: 7677-24-9 | C4H9NSi | 99.21 g/mol

Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.

Solubility
Miscible with organic solvents.

Notes
Moisture sensitive. Store in a cool place.Incompatible with water, strong oxidizing agents, strong reducing agents, strong acids and strong bases.

Specifications

Chemical Identifiers

• CAS: 7677-24-9
• Molecular Formula: C4H9NSi
• Molecular Weight (g/mol): 99.21
• MDL Number: MFCD00001765
• InChI Key: LEIMLDGFXIOXMT-UHFFFAOYSA-N
• Synonym: trimethylsilyl cyanide, cyanotrimethylsilane, trimethylsilanecarbonitrile, trimethylsilylcyanide, silanecarbonitrile, trimethyl, trimethylsilylnitrile, tmscn, trimethyl silane cyanide, trimethylsilylcarbonitrile, tms cyanide
• PubChem CID: 82115
• IUPAC Name: trimethylsilylformonitrile
• SMILES: C[Si](C)(C)C#N

• Boiling Point: 118°C to 119°C
• Melting Point: 11°C to 12°C
• Quantity: 100 g
• UN Number: UN3383
• Beilstein: 1737612
• Flash Point: 1°C (33°F)
• Solubility Information: Miscible with organic solvents.
• Formula Weight: 99.21
• Percent Purity: 97%
• Odor: Almond-like
• Refractive Index: 1.391
• Sensitivity: Moisture sensitive
• Density: 0.783
• Chemical Name or Material: Trimethylsilyl cyanide

Safety and Handling

Hazard Category	H225-H300+H310+H330
Hazard Statement	GHS H Statement H225-H300-H310-H330 Highly flammable liquid and vapour. Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P260-P262-P264b-P270-P271-P280-P284-P301+P310-P303+P361+P353-P304+P340-P310-P330-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC BY INHALATION LIQUID, FLAMMABLE, N.O.S.
EINECSNumber	231-657-3
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only