Trimethylsilyl isothiocyanate, 94%

Description

CAS: 2290-65-5 | C4H9NSSi | 131.268 g/mol

Trimethylsilyl isothiocyanate is used as derivatizing reagent during the synthesis of amino acid thiohydantoins. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylsilyl isothiocyanate is used as derivatizing reagent during the synthesis of amino acid thiohydantoins. It participates in ring opening reaction of N-substituted aziridines and cyclohexene oxide.

Solubility
Reacts with water.

Notes
Moisture Sensitive. Incompatible materials are Strong oxidizing agentsAlcohols, Strong bases, Amines, acids.

Specifications

Chemical Identifiers

• CAS: 2290-65-5
• Molecular Formula: C4H9NSSi
• Molecular Weight (g/mol): 131.268
• MDL Number: MFCD00004797
• InChI Key: XLTUPERVRFLGLJ-UHFFFAOYSA-N
• Synonym: trimethylsilyl isothiocyanate, silane, isothiocyanatotrimethyl, trimethylsilylisothiocyanate, isothiocyanato trimethyl silane, tmsisothiocyanate, tms-isothiocyanate, acmc-1clhj, trimethylsilyl-isothiocyanate, trimethylsilyl isothio-cyanate
• PubChem CID: 75297
• IUPAC Name: isothiocyanato(trimethyl)silane
• SMILES: C[Si](C)(C)N=C=S

• Melting Point: -33°C
• Density: 0.932
• Boiling Point: 143°C to 144°C
• Flash Point: 29°C (84°F)
• Odor: Pungent
• Refractive Index: 1.482
• Quantity: 5 g
• UN Number: UN1992
• Beilstein: 1745262
• Sensitivity: Moisture sensitive; May form a precipitate
• Solubility Information: Reacts with water.
• Formula Weight: 131.27
• Percent Purity: 94%
• Chemical Name or Material: Trimethylsilyl isothiocyanate

Safety and Handling

Hazard Category	H226-H301+H311+H331-H315-H319-H334-H335
Hazard Statement	GHS H Statement H301-H331-H226-H315-H319-H335 Toxic if swallowed. Toxic if inhaled. Flammable liquid and vapor. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P240-P243-P261-P264b-P270-P271-P280-P285-P301+P310-P303+P361+P353-P304+P341-P305+P351+P338-P311-P312-P330-P332+P313-P363-P374-P380-P501c
DOTInformation	Hazard Class: 3; Packaging Group: II
EINECSNumber	218-929-7
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only