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Medchemexpress LLC Tripeptide epoxyketone immunoproteasome (LMP-7) inhibitor | 1416709-79-9 | 98.9% | 618.72 g/mol | C37H38N4O5 | 50MG
Supplier: Medchemexpress LLC HY12358750MG
A selective tripeptide epoxyketone inhibitor of the immunoproteasome LMP7 subunit for biochemical and cellular research. It covalently modifies proteasomal N-terminal threonine active sites and has demonstrated antitumor activity in preclinical studies.
- Selective LMP7 (β5i) immunoproteasome inhibitor.
- Covalently modifies N-terminal threonine active sites.
- Reported IC50 of 22 nM against LMP7.
- Demonstrated inhibition of multiple myeloma cell growth and induction of apoptosis.
- High chemical purity (98.9%).
- Enantiomeric excess 100%.
- Molecular weight 618.72 g/mol and formula C37H38N4O5.
- Supplied in small research pack sizes, e.g., 50 mg.
- For research use only; not for human use.
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