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AdipoGen Triptolide

Supplier: AdipoGen CDXT0237M005
Chemical. CAS 38748-32-2. Formula C20H24O6. MW 360.4. Synthetic. Potent immunosuppressant with anti-inflammatory and antitumor properties. Exhibits potent antiproliferative activity, induces apoptosis, modulates autophagy and inhibits cell cycle regulators. Inhibits global gene transcription by inducing degradation of RNA polymerase II Pol II and by inhibiting the ATPase activity of XPB a subunit of the general transcription factor TFIIH. Interferes with a number of transcription factors including p53, NF-kappaB, nuclear factor of activated T cells NFAT and heat shock factor protein 1 HSF-1. Shown to inhibit aromatase activity.
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