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Cayman Chemical TrIptonIde 10mg

Supplier: Cayman Chemical 2915610 MG
A diterpenoid with diverse biological activities; inhibits IL-2 production and DNA synthesis in phytohemagglutinin-stimulated T cells (EC50s = 2.46 and 3.2 ng/ml, respectively); inhibits the proliferation of PC3, DU145, and LNCaP cells (IC50s = 11.96, 10.26, 12.01 nM, respectively); induces cell cycle arrest at the G2/M phase and increases apoptosis in PC3 cells in a concentration-dependent manner; reduces tumor growth in a PC3 mouse xenograft model at 10 mg/kg per day
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