Thermo Scientific Chemicals Tris(hydroxymethyl)aminomethane hydrochloride, 99+%

Description

CAS: 1185-53-1 | C4H12ClNO3 | 157.594 g/mol

Tris(hydroxymethyl)aminomethane hydrochloride is used as a component of buffer solutions in biology, biochemistry and molecular biology. It is also used for crystallization of proteins at various pH values. Further, it inhibits motor responses to adrenergic motor nerve stimulation in smooth muscles. In addition to this, it is used in coelomic fluid and in cortland medium to store unfertilized rainbow trout eggs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tris(hydroxymethyl)aminomethane hydrochloride is used as a component of buffer solutions in biology, biochemistry and molecular biology. It is also used for crystallization of proteins at various pH values. Further, it inhibits motor responses to adrenergic motor nerve stimulation in smooth muscles. In addition to this, it is used in coelomic fluid and in cortland medium to store unfertilized rainbow trout eggs.

Solubility
Soluble in water.

Notes
Hygroscopic. Incompatible with strong oxidizing agents, strong acids and bases.

Specifications

Chemical Identifiers

• CAS: 1185-53-1
• Molecular Formula: C4H12ClNO3
• Molecular Weight (g/mol): 157.594
• MDL Number: MFCD00012590
• InChI Key: QKNYBSVHEMOAJP-UHFFFAOYSA-N
• Synonym: tris hydrochloride, tris hydroxymethyl aminomethane hydrochloride, 2-amino-2-hydroxymethyl propane-1,3-diol hydrochloride, tromethamine hydrochloride, tris hcl, Tris-HCl, 2-amino-2-hydroxymethyl-1,3-propanediol hydrochloride, tris buffer hydrochloride, 1,3-propanediol, 2-amino-2-hydroxymethyl-, hydrochloride
• PubChem CID: 93573
• IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
• SMILES: C(C(CO)(CO)N)O.Cl

• Melting Point: ∼152°C (decomposition)
• pH: 3.5 to 5.0
• Linear Formula: (HOCH₂)₃CNH₂·HCl
• Quantity: 250 g
• Beilstein: 3675235
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water.
• Formula Weight: 157.6
• Percent Purity: ≥99%
• Chemical Name or Material: Tris (hydroxymethyl)aminomethane hydrochloride

Safety and Handling

Hazard Category	H315-H319-H335
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	214-684-5
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only