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Cayman Chemical TrndolaprIl 50mg
Supplier: Cayman Chemical 1352250 MG
A prodrug form of trandolaprilat; inhibits angiotensin I-induced pressor responses in rats and dogs (ID50s = 13.1 and 21.1 μg/kg, respectively); potentiates the bradykinin-induced depressor response in rats (ED50 = 5.5 μg/kg); decreases systolic and diastolic arterial pressure in dogs at 0.1, 0.3, and 1 mg/kg; decreases MAP and LVEDP in a rat model of left coronary artery occlusion-induced heart failure at 3 mg/kg; increases survival in stroke-prone spontaneously hypertensive rats fed a high-salt diet
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