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Cayman Chemical TrndolaprIlathydrate 10mg
Supplier: Cayman Chemical 2957710 MG
An ACE inhibitor; inhibits angiotensin I-induced contraction in isolated rat thoracic aorta (IC50 = 6.9 nM); potentiates bradykinin-induced contraction in isolated guinea pig ileum (AC50 = 2.7 nM); induces relaxation of norepinephrine- or potassium chloride-precontracted isolated rat thoracic aorta with intact endothelium in a concentration-dependent manner; inhibits angiotensin I-induced pressor responses in rats and dogs (ID50s = 9.9 and 7.2 μg/kg, respectively); potentiates the bradykinin-induced depressor response in rats (ED50 = 4.1 μg/kg)
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