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Cayman Chemical trns-PetroselInIc AcId 100mg
SDP

Supplier:  Cayman Chemical 20026100 MG

Encompass_Preferred

A potent inhibitor of PDE10A (IC50 1 26 nM for the human recombinant enzyme) selective for PDE10A over other PDEs with IC50 values ranging from 1 7 to 10 M increases cAMP and cGMP production as well as phosphorylation of CREB and GluR1 in mouse striatum in a dose-dependent manner reduces apomorphine-induced climbing behavior in mice (ID50 0 375 mg/kg) and disrupts the conditioned avoidance response in mice and rats (ID50s 0 441 and 1 079 mg/kg respectively) reverses ( )-MK-801-induced deficits in prepulse inhibition and social odor recognition in rats

Catalog No. 50-298-3104


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