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Cayman Chemical trns-VaccenIc AcId-d13 10mg
Supplier: Cayman Chemical 2771710 MG
An orally bioavailable inhibitor of mitochondrial complex I inhibits the ubiquinone reduction activity of isolated murine mitochondrial complex I at 60 nM reduces basal and spare respiratory capacities and increases glycolytic flux in primary CLL cells at 100 nM induces apoptosis in CLL cells grown under low glucose conditions or when administered in combination with 2-deoxy-D-glucose induces tumor regression in a glycolysis-deficient NB1 mouse xenograft model when administered at doses of 5 and 10 mg/kg
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