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Cayman Chemical TrnscrIptIon Factr STAT 96 1ea
SDP

Supplier:  Cayman Chemical 6017341 EA

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A peptide MC4R agonist increases intracellular cAMP levels in CHO cells expressing MC4R (EC50 0.42 nM) selectively binds to MC4R over MC3R and MC5R (IC50s 0.58 55 and 2.4 nM respectively) increases MAP pulse pressure and respiratory rate in a rat model of hemorrhagic shock in a dose-dependent manner and prevents multiple organ damage and increases survival in the same model

Catalog No. 50-289-2679


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