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Cayman Chemical TroglItazon 100mg
SDP

Catalog No. 502893915
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A selective agonist of PPARγ (EC50s = 0.78 and 0.55 μM for the mouse and human receptors, respectively, in a transactivation assay); selective for PPARγ over PPARα and PPARδ, at which it is inactive at ≤10 μM; exhibits antihyperglycemic and antihyperlipidemic properties in Zucker diabetic fatty rats, reducing plasma glucose and triglyceride levels by 61 and 87% respectively, at 500 mg/kg twice per day; induces cell cycle arrest at the G1 phase in SK-HEP-1 and Hep3B hepatocellular carcinoma cells at 10 μM and increases apoptosis in these cells at ≥30 μM

Catalog No. 50-289-3915 Supplier Cayman Chemical Supplier No. 71750100 MG
May include imposed supplier surcharges.
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A selective agonist of PPARγ (EC50s = 0.78 and 0.55 μM for the mouse and human receptors, respectively, in a transactivation assay); selective for PPARγ over PPARα and PPARδ, at which it is inactive at ≤10 μM; exhibits antihyperglycemic and antihyperlipidemic properties in Zucker diabetic fatty rats, reducing plasma glucose and triglyceride levels by 61 and 87% respectively, at 500 mg/kg twice per day; induces cell cycle arrest at the G1 phase in SK-HEP-1 and Hep3B hepatocellular carcinoma cells at 10 μM and increases apoptosis in these cells at ≥30 μM

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