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Cayman Chemical TrovafloxacInmesylate 10mg
SDP

Supplier:  Cayman Chemical 900030310 MG

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An SKP2 inhibitor reduces SKP2 levels and induces the accumulation of p27Kip1 and p21Cip21 in LNCaP-S14 cells at 40 UM cytotoxic to LNCaP-S14 cells (IC50 1.09 UM) but not non-cancerous IMR-90 human fibroblasts also targets cyclin D1 for proteasomal degradation as well as induces the unfolded protein response oxidative stress apoptosis and cell cycle arrest at the G1 phase in LNCaP-S14 cells reduces immobility time in the forced swim test and tail suspension test as well as increases the preference for sucrose in the sucrose preference test in a mouse model of chronic unpredictable stress-induced depression at 2 mg/kg

Catalog No. 50-289-2653


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