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Bachem (Trp63,Trp64)-C3a (63-77) Trifluoroacetate

Supplier: Bachem 4016370.0001
(Trp63,Trp64)-C3a (63-77) Trifluoroacetate, H-Trp-Trp-Gly-Lys-Lys-Tyr-Arg-Ala-Ser-Lys-Leu-Gly-Leu-Ala-Arg-OH, 130154-64-2, C86H134N26O18, Mr 1820.17, 1mg. (Trp63,Trp64)-C3a (63-77), synthetic superagonist analog of complement 3a, exhibited the greatest biological potency of all peptides tested. The peptide was 12-15 times more active than natural C3a. Such an optimal potency was obtained by introducing a bulky hydrophobic group such as Trp-Trp which binds more strongly to the hydrophobic site on the receptor than does the corresponding site on the natural ligand.
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