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Medchemexpress LLC Tryptamine guanosine carbamate | 1414808-96-0 | 99.8% | 469.45 | 25 MG
Supplier: Medchemexpress LLC 25MGHY138885
Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor with a Ki of 34 μM and a Kd of 3.65 μM. It significantly enhances morphine antinociception and prevents the development of tolerance. It has also been shown to reduce NMDAR activity and alleviate mechanical allodynia. This product is for research use only.
- Selective HINT1 inhibitor (Ki=34 μM, Kd=3.65 μM)
- Enhances morphine antinociception and prevents tolerance
- Reduces NMDAR activity promoted by morphine
- Attenuates NMDAR function and alleviates mechanical allodynia
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