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Medchemexpress LLC Tryptamine guanosine carbamate (TpGc) | 1414808-96-0 | MFCD00078028 | 99.8% | 469.45 | 1 MG
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Supplier:  Medchemexpress LLC HY1388851MG

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Tryptamine guanosine carbamate (TpGc) is a selective inhibitor of HINT1 (histidine triad nucleotide-binding protein 1). It significantly enhances morphine antinociception and helps prevent the development of tolerance. This compound is for research use only.

  • Selective HINT1 inhibitor (Ki=34 μM, Kd=3.65 μM)
  • Enhances morphine antinociception
  • Prevents development of acute antinociceptive tolerance
  • Reduces recruitment of NMDAR activity promoted by morphine
  • Attenuates NMDAR function and alleviates mechanical allodynia in chronic constriction injury models

Catalog No. 50-003-50074


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