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Enzo Life Sciences Tryptanthrin (5mg). CAS: 13220-57-0

Supplier: Enzo Life Sciences ALX270360M005
Potent inhibitor of prostaglandin and leukotriene synthesis in various cell lines. Selective inhibitor of cyclooxygenase 2 (COX-2). Inhibitor of inducible nitric oxide synsthase (iNOS; NOS II) expression. Inhibits the production of IFN-γ and IL-2 after stimulation of Peyer's patch lymphocytes with staphylococcal enterotoxin B (SEB). Inhibits P-glycoprotein (Pgp) (expressed by the MDR1 gene) and reverses doxorubicin (BML-GR319) resistance on breast cancer cells. Formula: C15H8N2O2. MW: 248.2. Purity: ≥98% (1H-NMR, HPLC). Solubility: Soluble in DMSO (8mg/ml) or methanol (0.3mg/ml); sparingly soluble in water (2.5µg/ml). Long Term Storage: +4°C.
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