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Abcam Tryptanthrin, immunomodulator, 25MG
Supplier: Abcam AB26988425MG
MW 248.24 Da. Indoloquinazoline alkaloid with broad pharmacological activity. Immunomodulatory activity. Blocks BV2 microglia activation in response to LPS. Inhibits pro-inflammatory cytockine production via Nrf2, HO-1 and NFκB pathways. Inhibits indoleamine 2,3-dioxygenase 2 (IC₅₀ = 5-17 μM). Promotes neuronal differentiation of human neuroblastoma cells. Also reported to have anti-cancer, anti-microbial and anti-oxidant activity.
The product is subject to the following: Abcam Restricted Use Statement
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