ProSci Tryptase epsilon Recombinant Protein

Catalog No.	Quantity
16-594-229	0.05 mg

Catalog No. 16-594-229 Supplier ProSci Supplier No. 913510050

Description

Recombinant Protein

This recombinant protein can be used for biological assays. For research use only.

Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP-4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, alpha1-antitrypsin and secretory leukocyte protease inhibitor. BSSP-4 efficiently converts pro-urokinase- type plasminogen activator to its mature, active form.

Specifications

• Accession Number: Q9GZN4
• Gene ID (Entrez): 64063
• Molecular Weight (g/mol): 31.56 kDa
• Quantity: 0.05 mg
• Source: Human Cells
• Common Name: protease, serine 22
• Gene Symbol: PRSS22
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: C-6 His tag
• Sequence: Ala33-Ser317
• Content And Storage: Store at -20°C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Purity or Quality Grade: >95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
• Synonym: Brain-Specific Serine Protease 4, BSSP-4, Serine Protease 22, Serine Protease 26, Tryptase Epsilon, PRSS22, BSSP4, PRSS26