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STEMCELL Technologies TTNPB, Size: 10 mg
SDP

Catalog No. 501975997
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TTNPB is an analog of retinoic acid that potently and selectively activates retinoic acid receptors (RAR; EC₅₀ = 21, 4, and 2.4 nM for RARα, RARβ, and RARγ, respectively; Beard et al.; Wong et al.).DIFFERENTIATION· In combination with CHIR99021 or Activin A, induces intermediate mesoderm formation from human or mouse pluripotent stem cells, respectively (Araoka et al.; Oeda et al.).· Promotes neuronal differentiation in cultured chick caudal neural plate explants (Diez del Corral et al.). REPROGRAMMING· Enables chemical reprogramming (without genetic factors) of mouse embryonic fibroblasts to induced pluripotent stem (iPS) cells, in combination with CHIR99021, Tranylcypromine, Valproic Acid, 3-Deazaneplanocin A, and E-616452 (Hou et al.).CANCER RESEARCH· Induces the in vitro growth and differentiation to granulocytes of myeloid progenitors isolated from myelodysplastic syndrome (MDS) patients (Fabian et al.).

Catalog No. 50-197-5997 Supplier STEMCELL Technologies Supplier No. 72892
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TTNPB is an analog of retinoic acid that potently and selectively activates retinoic acid receptors (RAR; EC₅₀ = 21, 4, and 2.4 nM for RARα, RARβ, and RARγ, respectively; Beard et al.; Wong et al.).DIFFERENTIATION· In combination with CHIR99021 or Activin A, induces intermediate mesoderm formation from human or mouse pluripotent stem cells, respectively (Araoka et al.; Oeda et al.).· Promotes neuronal differentiation in cultured chick caudal neural plate explants (Diez del Corral et al.). REPROGRAMMING· Enables chemical reprogramming (without genetic factors) of mouse embryonic fibroblasts to induced pluripotent stem (iPS) cells, in combination with CHIR99021, Tranylcypromine, Valproic Acid, 3-Deazaneplanocin A, and E-616452 (Hou et al.).CANCER RESEARCH· Induces the in vitro growth and differentiation to granulocytes of myeloid progenitors isolated from myelodysplastic syndrome (MDS) patients (Fabian et al.).

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