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Cayman Chemical ttramthyl NordIhydroguaIr 50mg
Supplier: Cayman Chemical 7030250 MG
A derivative of nordihydroguaiaretic acid; inhibits Tat-regulated HIV promoter transactivation in COS-1 cells in a reporter assay (IC50 = 11 µM); inhibits replication of acyclovir-sensitive and -resistant strains of HSV-1 in Vero cells (IC50s = 5.6 and 8.9 µM, respectively); induces cell cycle arrest at the G1/G0 phase in A375 cells at 50 µM; inhibits tumor growth in an A375 mouse xenograft model at 250 mg/kg; inhibits tumor growth in a B16 murine melanoma model at 166 mg/kg
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