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Apexbio Technology LLC Tubastatin A HCl, 50mg CAS# 1310693-92-5
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Supplier:  Apexbio Technology LLC A854750

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Tubastatin A HCl is a selective inhibitor of HDAC6 with IC50 value of 15 nM [1]. HDAC6 (histone deacetylase 6) is an enzyme and plays an important role in a variety of processes, including transcriptional regulation, cell cycle preogression and developmental events. Abnormal expression of HDAC6 is correlated with many kinds of diseases, including Alzheimer's disease and cancers [1]. Tubastatin A HCl is a potent HDAC6 inhibitor and has the most selective compared with other HDAC isoforms. When tested with primary cortical neuron cells, Tubastatin A HCl treatment protected HCA-induced neuronal cell death in a dose range from 5 M to 10 M. Other sizes are also available. Please inqury us for quote.

Catalog No. 50-199-8399


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