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Cayman Chemical TubeImosIde I 25mg
Supplier: Cayman Chemical 2227625 MG
A triterpenoid saponin natural product; has antiproliferative activity against HepG2 (IC50s = 15.5 μM) and HeLa cells (IC50 = 25 μM); induces nuclear condensation and fragmentation, cell cycle arrest, mitochondrial membrane disruption, and apoptosis; decreases tumor volume and microvessel density in vivo in NCI-H460 flank xenografts (5 mg/kg); decreases metastasis and CXCR4 in vivo in a breast cancer MDA-MB-231 model
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