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Medchemexpress LLC Tulobuterol (C-78 free base) | 41570-61-0 | 99.7% | 50 MG
Supplier: Medchemexpress LLC HYB181050MG
Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. It is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength.
- Decreases RV14 RNA levels at 1 day and 3 days after infection in human tracheal epithelial cells.
- Significantly lowers sICAM-1 concentrations in cell supernatants.
- Reduces the number and fluorescence intensity of acidic endosomes.
- Decreases RV14 infection-induced secretion of IL-1β, IL-6, and IL-8.
- Produces a small but significant reduction in p50, p65, and c-Rel of NF-κB induced by RV14 infection.
- Maintains diaphragm muscle contractility for over 24 hours in a mouse model of sepsis.
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