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Abcam TW-37, 10MG

Supplier:  Abcam AB27349010MG

Encompass_Preferred

MW 573.7 Da, Purity >98%. Small-molecule inhibitor of BCL-2 (Ki = 0.29 μM). Inhibits multiple BCL-2 family members including BCL-XL (Ki = 1.11 μM) and MCL-1 (Ki= 0.26 μM). Binds to the BCL-2 homology domain 3 (BH3) groove of BCL-2. Significant anti-proliferative and pro-apoptotic activity in lymphoma cells.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-268-2952


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