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Eurofins Discoverx TYK2, active, 10 µg. (14-924)
Supplier: Eurofins Discoverx 14924
N-terminal 6xHis-tagged recombinant, human TYK2 amino acids 875-end. TYK2 is member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. For detailed product information, visit www.discoverx.com/proteins.
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