Invitrogen™ Human TYK2, GST Tag Recombinant Protein

Catalog No.	Quantity
PV4790	10 μg
PR8440C	100 μg

Catalog No. PV4790 Supplier Invitrogen™ Supplier No. PV4790

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Cytoplasmic, Catalytic.

Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Specifications

• Accession Number: P29597
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 0.02% Triton X-100, 50% glycerol, 2mM DTT, 0.5mM EDTA, 150mM NaCl and no preservative; pH 7.5
• Gene ID (Entrez): 7297
• Molecular Weight (g/mol): 68.8 kDa
• Name: Human TYK2, GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; IMD35; JTK1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2; Tyk2; tyrosine kinase 2; tyrosine kinase TYK2
• Common Name: TYK2
• Gene Symbol: TYK2
• Kinase Family: JAK Kinase Family
• Protein Length: 833-1187
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: 833-1187
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
• Kinase Group: Tyrosine Kinases
• Shipping Condition: Dry Ice
• System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™
• Tag Position: N-Terminal
• Target Entry: TYK2
• Target Gene: tyrosine kinase 2
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Cytoplasmic, Catalytic
• Form: Liquid
• Protein Subtype: Cytoplasmic Tyrosine Kinases
• Research Category: Signal Transduction