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Medchemexpress LLC Tyrphostin AG 879 | 148741-30-4 | 99.3% | 316.46 | 50 MG
Supplier: Medchemexpress LLC HY2087850MG
Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC. It also acts as a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 μM, demonstrating at least 500-fold higher selectivity to ErbB2 than EGFR. This compound exhibits anticancer activity.
- Tyrosine kinase inhibitor
- Inhibits TrKA phosphorylation (IC50 of 10 μM), but not TrKB and TrKC
- Selective ErbB2 tyrosine kinase inhibitor (IC50 of 1 μM)
- At least 500-fold higher selectivity to ErbB2 than EGFR
- Anticancer activity
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